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bioderma Matricium

bioderma Bioderma Matricium lists 61 ingredients on its label, 60 decoded. See what each one does, its irritancy and comedogenic tendency, and its status in national inventories.

Ingredients overview

Label order. Colour is our internal rating: green routine, yellow restricted or worth a look, red prohibited or high-risk, grey not yet decoded.

Ingredients are listed in label order; the order reflects the label only, not exact concentrations.

  1. Aqua/Water/Eau
  2. Sodium Chloride
  3. Glucose
  4. Sodium Hyaluronate
  5. Alanyl Glutamine
  6. Disodium Phosphate
  7. Arginine Hcl
  8. Sodium Acetate
  9. Lactis Proteinum/Whey Protein/Proteine Du Petit Lait
  10. Serine
  11. Leucine
  12. Magnesium Chloride
  13. Potassium Chloride
  14. Mannitol
  15. Fructooligosaccharides
  16. Rhamnose
  17. Xylitol
  18. Valine
  19. Sodium Pyruvate
  20. Lysine Hcl
  21. Histidine Hcl
  22. Proline
  23. Cysteine Hcl
  24. Hydroxyproline
  25. Glutamic Acid
  26. Asparagine
  27. Threonine
  28. Inositol
  29. Adenine
  30. Alanine
  31. Aspartic Acid
  32. Glycine
  33. Methionine
  34. Tyrosine
  35. Phenylalanine
  36. Tryptophan
  37. Lactic Acid
  38. Isoleucine
  39. Sodium Sulfate
  40. Folic Acid
  41. Ferrous Sulfate
  42. Calcium Pantothenate
  43. Thiamine Hcl
  44. Pyridoxine Hcl
  45. Niacinamide
  46. Ascorbic Acid
  47. Thymidine
  48. Cyanocobalamin
  49. Thioctic Acid
  50. Riboflavin
  51. Sodium Metasilicate
  52. Zinc Sulfate
  53. Adenosine
  54. Guanine
  55. Deoxyribose
  56. Ribose
  57. Biotin
  58. Ammonium Molybdate
  59. Ammonium Vanadate
  60. Copper Sulfate
  61. Manganese Chloride

Highlights

Free of alcoholFree of parabensFree of siliconesFree of sulfatesFree of mineral oilFree of essential oilsFree of formaldehyde releasersContains fragrance

Formulation view Oil-free aqueous formula with glucose, oligosaccharides, and amino acids mimicking NMF. Factory observation: The high concentration of water-soluble nutrients poses significant microbial risks, demanding stringent aseptic filling and robust preservation controls.E · AI inference · to be verified

Key ingredients

溶剂
Aqua/Water/Eau
BULKING
Sodium Chloride
HUMECTANT
GlucoseSodium HyaluronateAlanyl Glutamine
ANTICORROSIVE
Disodium Phosphate
SKIN CONDITIONING
Arginine Hcl
BUFFERING
Sodium Acetate

Other ingredients

Lactis Proteinum/Whey Protein/Proteine Du Petit LaitSerineLeucineMagnesium ChloridePotassium ChlorideMannitolFructooligosaccharidesRhamnoseXylitolValineSodium PyruvateLysine HclHistidine HclProlineCysteine HclHydroxyprolineGlutamic AcidAsparagineThreonineInositolAdenineAlanineAspartic AcidGlycineMethionineTyrosinePhenylalanineTryptophanLactic AcidIsoleucineSodium SulfateFolic AcidFerrous SulfateCalcium PantothenateThiamine HclPyridoxine HclNiacinamideAscorbic AcidThymidineCyanocobalaminThioctic AcidRiboflavinSodium MetasilicateZinc SulfateAdenosineGuanineDeoxyriboseRiboseBiotinAmmonium MolybdateAmmonium VanadateCopper SulfateManganese Chloride

Skim through

IngredientWhat it doesIrr. · Com.Rating
Aqua/Water/Eau溶剂0 · –Green
Sodium ChlorideBULKING, FRAGRANCE, ORAL CARE, VISCOSITY CONTROLLING0 · –Green
GlucoseHUMECTANT0 · –Green
Sodium HyaluronateHUMECTANT, SKIN CONDITIONING0 · 0Green
Alanyl GlutamineHUMECTANT, SKIN CONDITIONING0 · –Green
Disodium PhosphateANTICORROSIVE, BUFFERING, FRAGRANCE1 · –Green
Arginine HclSKIN CONDITIONING0 · –Green
Sodium AcetateBUFFERING, FRAGRANCE0 · –Green
Lactis Proteinum/Whey Protein/Proteine Du Petit LaitNot decoded yet
SerineANTISTATIC, HAIR CONDITIONING, FRAGRANCE, SKIN CONDITIONING0 · –Green
LeucineANTISTATIC, HAIR CONDITIONING, SKIN CONDITIONING0 · –Green
Magnesium ChlorideVISCOSITY CONTROLLING, FLAVOURING0 · –Green
Potassium ChlorideVISCOSITY CONTROLLING2 · –Green
MannitolBINDING, HUMECTANT, FRAGRANCE, MOISTURISING, SKIN CONDITIONING0 · –Green
FructooligosaccharidesHUMECTANT, SKIN CONDITIONING0 · –Green
RhamnoseHUMECTANT, FRAGRANCE0 · –Green
XylitolANTI-SEBORRHEIC, DEODORANT, HUMECTANT, FLAVOURING, SKIN CONDITIONING - HUMECTANT0 · –Green
ValineANTISTATIC, HAIR CONDITIONING, FRAGRANCE, SKIN CONDITIONING0 · –Green
Sodium PyruvateSKIN CONDITIONING, BUFFER0 · –Green
Lysine HclHAIR CONDITIONING, SKIN CONDITIONING0 · –Green
Histidine HclHAIR CONDITIONING, SKIN CONDITIONING0 · –Green
ProlineHAIR CONDITIONING, SKIN CONDITIONING0 · –Green
Cysteine HclNot decoded yet
HydroxyprolineANTISTATIC, HAIR CONDITIONING, SKIN CONDITIONING, SURFACTANT - CLEANSING0 · –Green
Glutamic AcidANTISTATIC, HAIR CONDITIONING, HUMECTANT0 · –Green
AsparagineANTISTATIC, HAIR CONDITIONING, FRAGRANCE, SKIN CONDITIONING0 · –Green
ThreonineANTISTATIC, HAIR CONDITIONING, HAIR WAVING OR STRAIGHTENING0 · –Green
InositolANTISTATIC, HAIR CONDITIONING, HUMECTANT0 · –Green
AdenineSKIN CONDITIONING0 · –Green
AlanineANTISTATIC, HAIR CONDITIONING, FRAGRANCE, SKIN CONDITIONING0 · –Green
Aspartic AcidANTISTATIC, HAIR CONDITIONING, FRAGRANCE, SKIN CONDITIONING0 · –Green
GlycineANTISTATIC, BUFFERING, HAIR CONDITIONING, SKIN CONDITIONING0 · –Green
MethionineANTISTATIC, HAIR CONDITIONING, SKIN CONDITIONING0 · –Green
TyrosineANTISTATIC, HAIR CONDITIONING, FRAGRANCE, SKIN CONDITIONING0 · –Green
PhenylalanineHAIR CONDITIONING, FRAGRANCE, SKIN CONDITIONING0 · –Green
TryptophanANTISTATIC, HAIR CONDITIONING, FRAGRANCE0 · –Green
Lactic AcidBUFFERING, HUMECTANT, SKIN CONDITIONING1 · –Green
IsoleucineANTISTATIC, HAIR CONDITIONING, SKIN CONDITIONING0 · –Green
Sodium SulfateBULKING, VISCOSITY CONTROLLING0 · –Green
Folic AcidSKIN CONDITIONING0 · –Green
Ferrous SulfateNot decoded yet3 · –
Calcium PantothenateHAIR CONDITIONING, SKIN CONDITIONING - MISCELLANEOUS0 · –Green
Thiamine HclFRAGRANCE, SKIN CONDITIONING0 · –Green
Pyridoxine HclANTISTATIC, HAIR CONDITIONING, SKIN CONDITIONING0 · –Green
NiacinamideSMOOTHING0 · –Green
Ascorbic AcidANTIOXIDANT, BUFFERING, FRAGRANCE, SKIN CONDITIONING2 · –Green
ThymidineSKIN CONDITIONING0 · –Green
CyanocobalaminSKIN CONDITIONING0 · –Green
Thioctic AcidANTIOXIDANTGreen
RiboflavinCOLORANT, SKIN CONDITIONING - MISCELLANEOUS · 限制 IV/1450 · –Green
Sodium MetasilicateANTICORROSIVE, BUFFERING, CHELATING5 · –Green
Zinc SulfateANTIMICROBIAL, ANTIPLAQUE, ASTRINGENT, ORAL CARE · 限制 III/243 · –Green
AdenosineSKIN CONDITIONING0 · –Green
GuanineCOLORANT, OPACIFYING0 · –Green
DeoxyriboseNot decoded yet
RiboseHUMECTANT, SKIN CONDITIONING0 · –Green
BiotinHAIR CONDITIONING, SKIN CONDITIONING - MISCELLANEOUSGreen
Ammonium MolybdateSKIN CONDITIONING1 · –Yellow
Ammonium VanadateSKIN CONDITIONING1 · –Yellow
Copper SulfateSKIN CONDITIONING3 · –Yellow
Manganese ChlorideSKIN CONDITIONING1 · –Green

The comedogenic column only shows scores with a published source. A blank means "no public source", not "non-comedogenic".

Ingredients explained

Each note carries its evidence level: C comes from official inventories (NMPA names, CosIng functions, annex restrictions); E is AI inference nobody has checked yet — treat it as a candidate. How we grade evidence →

Aqua/Water/Eau
Water as solvent/base; main ingredient, microbial control needed, paired with preservatives.E · AI inference · to be verified
Sodium Chloride
Salt for gel viscosity control; used as precipitant in soapsE · AI inference · to be verified
Glucose
Low-MW humectant and buffer; high hygroscopicity requires careful preservation and humidity control.B · Third-party verified
Sodium Hyaluronate
Potent humectant at 0.1–2%; different MW for penetration depth, high levels may draw moistureC · Official source
Alanyl Glutamine
Dipeptide acting as humectant and skin conditioner; low molecular weight aids penetration; usually used in combination at low concentrations.E · AI inference · to be verified
Disodium Phosphate
Phosphate buffer for pH adjustment and preservation; water-soluble; high levels may irritate mucous membranes.B · Third-party verified
Arginine Hcl
Amphoteric amino acid salt, moisturizer and buffer; high levels may irritate sensitive skin.B · Third-party verified
Sodium Acetate
Sodium acetate buffer for pH adjustment; sometimes acts as mild fragrance, common in lotions and washesB · Third-party verified
Lactis Proteinum/Whey Protein/Proteine Du Petit Lait
Not decoded yet
Serine
Humectant amino acid, 1–3%; high water solubility, compatible with sensitive skin.B · Third-party verified
Leucine
Amino acid for antistatic and skin/hair conditioning; used at low concentrations.B · Third-party verified
Magnesium Chloride
Inorganic salt for thickening and pH adjustment; 0.1-1%, avoid calcium ionsE · AI inference · to be verified
Potassium Chloride
Viscosity modifier for gels and shampoos; high concentrations may cause local stinging.E · AI inference · to be verified
Mannitol
Polyol humectant with binding/skin conditioning properties; high levels may cause osmotic irritationB · Third-party verified
Fructooligosaccharides
Prebiotic polysaccharide for hydration/skin conditioning; high levels may feel stickyE · AI inference · to be verified
Rhamnose
Polysaccharide humectant for hydration; used at low levels, mild flavor aid.B · Third-party verified
Xylitol
Polyol humectant, sweet taste; water-soluble, high hygroscopy, excess draws moisture.B · Third-party verified
Valine
Amino acid humectant, common in amino acid cleansers and sprays; mild, suitable for all skin typesB · Third-party verified
Sodium Pyruvate
Alpha-keto acid salt; participates in energy metabolism, often an antioxidant booster; used at low concentrations to stabilize pH.E · AI inference · to be verified
Lysine Hcl
Lysine HCl, amino acid for hair and skin conditioning, reduces protein lossB · Third-party verified
Histidine Hcl
Amino acid salt for pH buffering and hair conditioning; gentle buffering system, potential sensitization at high concentrations.B · Third-party verified
Proline
Proline, amino-acid humectant; boosts stratum corneum hydration, stable at pH 4-5.B · Third-party verified
Cysteine Hcl
CIR 安全评估:Safety Assessment of alpha-Amino Acids as Used in CosmeticsB · Third-party verified
Hydroxyproline
Amino acid derivative for humectancy and skin conditioning; supports collagen metabolism, water-soluble, gentleE · AI inference · to be verified
Glutamic Acid
Glutamic acid, non-essential amino acid humectant; high levels can be astringent, buffer needed.B · Third-party verified
Asparagine
Non-protein amino acid for humectancy and antistatic effect; water-soluble, slight odor at high levels, check compatibility.B · Third-party verified
Threonine
Threonine, essential amino acid for hair/skin; blended with other AAs for balance.B · Third-party verified
Inositol
Humectant at 0.5–2%; gentle moisturizing, suitable for sensitive skinB · Third-party verified
Adenine
Purine base for skin conditioning; low use levels, good safety profileE · AI inference · to be verified
Alanine
Amino acid for antistatic and conditioning; low irritation, slight salty taste at high levelsB · Third-party verified
Aspartic Acid
Amino acid humectant and conditioner, common in rinse-off products; low levels mild, high levels may shift pHB · Third-party verified
Glycine
Humectant amino acid, 1–3%; small molecule, low irritation.B · Third-party verified
Methionine
Sulfur-containing amino acid for hair and skin conditioning; often used in combinations with other amino acids.B · Third-party verified
Tyrosine
Amino acid involved in melanin synthesis; used for hair conditioning.B · Third-party verified
Phenylalanine
Amino acid for hair and skin conditioning; usually part of a blend, no significant standalone efficacy dataB · Third-party verified
Tryptophan
Amino acid for conditioning and antistatic; faint odor.B · Third-party verified
Lactic Acid
AHA pH adjuster at 0.5-5%; exfoliation/humectancy, mild at low conc., irritating at high, avoid conflict with alkaline preservatives.B · Third-party verified
Isoleucine
Amino acid for hair and skin conditioning and antistatic purposes; often blended; check taste if high.B · Third-party verified
Sodium Sulfate
Inorganic salt for viscosity; high concentrations cause osmotic dehydration.B · Third-party verified
Folic Acid
Folic acid, Vitamin B9, used for skin conditioning to support cellular metabolismE · AI inference · to be verified
Ferrous Sulfate
Not decoded yet
Calcium Pantothenate
Pro-vitamin B5 for hair/skin conditioning; water-soluble, used in conditionersB · Third-party verified
Thiamine Hcl
Vitamin B1 hydrochloride; acts as conditioner and fragrance agent, used at low concentrations for skin health and metabolism.E · AI inference · to be verified
Pyridoxine Hcl
Vitamin B6 HCl; trace skin/hair conditioning/antiox; very mild, high-conc pigmentation debateE · AI inference · to be verified
Niacinamide
Niacinamide at 2–5%; improves texture, controls oil, brightens; high levels may cause sensitivityC · Official source
Ascorbic Acid
Vitamin C, potent antioxidant requiring acidic environment for stability; oxidizes and discolors easily, needs light and air protection, concentration 1-10%, pure L-ascorbic acid is more irritating.B · Third-party verified
Thymidine
DNA precursor used in cellular nutrition formulas; added in trace amounts to support epidermal repairE · AI inference · to be verified
Cyanocobalamin
Vitamin B12 derivative, antioxidant and skin conditioning; light-sensitive, requires light-protective packaging, water-solubleE · AI inference · to be verified
Thioctic Acid
Alpha-lipoic acid; potent antioxidant; poor water solubility, often used as ester derivativesC · Official source
Riboflavin
Vitamin B2 for color and skin care; photosensitive, requires light-shielding packagingE · AI inference · to be verified
Sodium Metasilicate
Sodium MetasilicateB · Third-party verified
Zinc Sulfate
Antimicrobial and astringent, restricted in oral care; <1% topical, metallic taste, avoid mixing with amino acidsB · Third-party verified
Adenosine
Skin conditioner at 0.1-1%; used for anti-aging and repairB · Third-party verified
Guanine
Purine base compound at 0.1-1%; provides pearlescent effect; gentle and safeE · AI inference · to be verified
Deoxyribose
Not decoded yet
Ribose
Ribose, humectant and skin conditioner; small molecule with high hygroscopicity, blend with other humectants.B · Third-party verified
Biotin
Vitamin B7 nutrient claimant; topical effect limited, use at 1-20 ppm.B · Third-party verified
Ammonium Molybdate
Molybdenum mineral salt used in trace amounts; trace element supplement at very low concentrations; high levels may be irritatingE · AI inference · to be verified
Ammonium Vanadate
Vanadium mineral salt used in trace amounts; trace element supplement at very low concentrations; high levels may be irritatingE · AI inference · to be verified
Copper Sulfate
Trace chelator and antioxidant booster; copper ions have antioxidant activity, not for high-level use to avoid irritationC · Official source
Manganese Chloride
Inorganic manganese salt; use <0.01% for trace element supplement, avoid excessE · AI inference · to be verified

Source: full ingredient list published on the product label, collected 2026-09-18. Ratings are our internal reading, not a regulatory conclusion. · Product page

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