CI 45370
氧化铁黄
Also known as 4',5'-Dibromo-3',6'-dihydroxyspiro[isobenzofuran-1(3H),9'-[9H]xanthene]-3-one
CAS 4372-02-5EC 224-468-2 / 209-876-0PubChem CID 20388
What it is and how it is used
Yellow inorganic pigment, provides stable color; safe and inert, does not penetrate skin, suitable for color cosmetics and SPF
Status in national inventories
| China · Inventory of existing ingredients | 00304 | 按照《化妆品安全技术规范》要求使用 |
|---|---|---|
| EU · CosIng | 32768 | 功能 COLORANT · 限制 IV/75 (CI 45370) II/1333 (Solvent Red 72) and its disodium salt (CI 45370) when used as a substance in hair dye products |
| ASEAN · Cosmetic Directive | ASEAN-IV/45370 | 附录 IV 准用着色剂 · Ref 45370 · CI 45370 · Orange · Not more than 1% 2-(6-hydroxy-3- oxo-3H-xanthen-9-yl) benzoic acid and 2% 2-(bromo-6-hydroxy-3-oxo- 3H-xanthen-9-yl)benzoic acid |
Matched on the exact INCI name; salts, esters and synonyms may be missed. The latest official text prevails.
Regulatory status by market Prohibited / restricted / permitted — listing is not approval
Asia-Pacific
| Market | Status | Conditions (as published) | Source |
|---|---|---|---|
ASEANASEAN Cosmetic CommitteeApplies in 10 countries / territoriesSingapore · Thailand · Malaysia · Indonesia · Philippines · Vietnam · Brunei · Cambodia · Laos · Myanmar | PermittedColorantACD Annex IV | 附录 IV 准用着色剂 · Ref 45370 · CI 45370 · Orange · Not more than 1% 2-(6-hydroxy-3- oxo-3H-xanthen-9-yl) benzoic acid and 2% 2-(bromo-6-hydroxy-3-oxo- 3H-xanthen-9-yl)benzoic acid | ASEAN Cosmetic Directive Annexes rel. 2026-06-10 (NPRA)C · Official source |
| KoreaMFDS | Restricted화장품 사용제한 원료 | 구분: 한도/금지; 표준명: CI 45370; CASNo: 4372-02-5, 596-03-2; 이명: Acid Orange 11, 4',5'-Dibromo-3',6'-Dihydroxyspiro[Isobenzofuran-1(3H),9'-[9H]Xanthen]-3-one, Disodium… Show full text구분: 한도/금지; 표준명: CI 45370; CASNo: 4372-02-5, 596-03-2; 이명: Acid Orange 11, 4',5'-Dibromo-3',6'-Dihydroxyspiro[Isobenzofuran-1(3H),9'-[9H]Xanthen]-3-one, Disodium Salt, 4',5'-Dibromofluorandiol, Disodium Salt, 4,5-Dibromofluorescein, Disodium 2-(4,5-Dibromo-6-Oxido-3-Oxoxanthen-9-yl)Benzoate, Orange No. 201, Spiro[Isobenzofuran-1(3H),9'-[9H]Xanthen]-3-one, 4',5'-Dibromo-3',6'-Dihydroxy-, Disodium Salt; 영문명: CI 45370 | kr-mfdsC · Official source |
Americas
| Market | Status | Conditions (as published) | Source |
|---|---|---|---|
MercosurGrupo Mercado ComúnApplies in 4 countries / territoriesBrazil · Argentina · Uruguay · Paraguay | PermittedColorantGMC 16/12 (colorantes) CI 45370 | Res. GMC 16/12 · NARANJA · X · No más de 1% de ácido 2-(6-hidroxi-3-oxo-3H-xantin-9-il)benzoico (fluoresceína) y 2% de ácido 2-(bromo-6-hidroxi-3-oxo-3H-xantin-9-il) benzoico (monobromofluoresceina) | Res. GMC 16/12 Lista de colorantes · normas.mercosur.intC · Official source |
EMEA
| Market | Status | Conditions (as published) | Source |
|---|---|---|---|
| United KingdomOPSS | PermittedColorantUK Annex IV | 4',5'-Dibromo-3',6'-dihydroxyspiro[isobenzofuran-1(3H),9'-[9H]xanthene]-3-one and its insoluble barium, strontium and zirconium lakes, salts and pigments · 4537… Show full text4',5'-Dibromo-3',6'-dihydroxyspiro[isobenzofuran-1(3H),9'-[9H]xanthene]-3-one and its insoluble barium, strontium and zirconium lakes, salts and pigments · 45370 · Orange · Not more than 1 % 2-(6-hydroxy-3-oxo-3H-xanthen-9-y1) benzoic acid and 2 % 2-(bromo-6-hydroxy-3-oxo-3H-xanthen-9-yl) benzoic acid · UK Annex IV · No 75 | UK Cosmetics Regulation (assimilated Regulation (EC) No 1223C · Official source |
Public regulatory text on file for 4 jurisdiction(s), covering 18 countries / territories once regional blocs are expanded. Other markets have no public data here — absence is neither approval nor prohibition. Table updated 2026-09-22.
Compiled from publicly published regulatory texts; conditions are reproduced as published, neither rewritten nor translated. The latest official announcement of the target market prevails — this table is a compiled reference, not a compliance conclusion. Matched on the INCI name; salts, esters and synonyms may be missed. Usability and labelling are for the brand and its responsible person to verify against the full text.
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Functions from EU CosIng and the China inventory; irritancy, comedogenicity and rating are our internal reading, not a regulatory conclusion. Structure and molecular data from PubChem.
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