What it is and how it is used
Highly active and unstable, needs robust antioxidant encapsulation; 0.1-1.0%, pregnancy contraindicated
Status in national inventories
| China · Inventory of existing ingredients | 06162 | leave-on 1% |
|---|---|---|
| EU · CosIng | 37479 | 功能 SKIN CONDITIONING - MISCELLANEOUS · 限制 III/376 |
| EU · Annexes to 1223/2009 | III/376 | 附录 III 限用 · 序号 376 · (a) Body lotion (b) other leave-on and rinse-off products / (a) 0,05 % Retinol Equivalent (RE) (b) 0,3 % RE · 标签措辞:For any cosmetic product containing Retinol, Retinyl Acetate or Retinyl Palmitate the following, labelli |
Matched on the exact INCI name; salts, esters and synonyms may be missed. The latest official text prevails.
Regulatory status by market Prohibited / restricted / permitted — listing is not approval
Asia-Pacific
| Market | Status | Conditions (as published) | Source |
|---|---|---|---|
| KoreaMFDS | Restricted화장품 사용제한 원료 | 구분: 한도; 표준명: 레티놀; CASNo: 11103-57-4 68-26-8; 이명: 3,7-Dimethyl-9-(2,6,6-Trimethyl-1-Cyclohexen-1-yl)-2,4,6,8-Nonatetraen-1-ol Dry Formed Vitamin A retinol (INN) Vitamin A vitaminum a (EP); 영문명: Retinol | kr-mfdsC · Official source |
Americas
| Market | Status | Conditions (as published) | Source |
|---|---|---|---|
| MexicoCOFEPRIS | RestrictedAcuerdo DOF numeral TERCERO (restringidas) nº 71 | TERCERO nº 71 · 3,7-Dimetil-9-(2,6,6-trimetil-1- ciclohexen-1-il)-2,4,6,8- nonatetraen- 1-ol Vitamina A · 0,15 (como retinol) · Para todo tipo de productos. | Acuerdo sustancias prohibidas y restringidas en productos deC · Official source |
| United States · CaliforniaCDPH | Listed onlyCSCP reportable ingredient | Reportable ingredient under the California Safe Cosmetics Act: reported to CDPH as known or suspected to cause cancer, birth defects, or other developmental or … Show full textReportable ingredient under the California Safe Cosmetics Act: reported to CDPH as known or suspected to cause cancer, birth defects, or other developmental or reproductive harm. Chemical name (as reported): Retinol; CAS 68-26-8; reported in 270 product records from 35 companies; top categories: Skin Care Products | Makeup Products (non-permanent) | Sun-Related Products; 7 records discontinued/reformulated; reports 2009-08-26..2020-03-12. | ca-cdphC · Official source |
EMEA
| Market | Status | Conditions (as published) | Source |
|---|---|---|---|
European UnionEuropean CommissionApplies in 30 countries / territoriesAustria · Belgium · Bulgaria · Croatia · Cyprus · Czechia · Denmark · Estonia · Finland · France · Germany · Greece · Hungary · Ireland · Italy · Latvia · Lithuania · Luxembourg · Malta · Netherlands · Poland · Portugal · Romania · Slovakia · Slovenia · Spain · Sweden · Norway · Iceland · Liechtenstein | RestrictedEU Annex III | 附录 III 限用 · 序号 376 · (a) Body lotion (b) other leave-on and rinse-off products / (a) 0,05 % Retinol Equivalent (RE) (b) 0,3 % RE · 标签措辞:For any cosmetic product… Show full text附录 III 限用 · 序号 376 · (a) Body lotion (b) other leave-on and rinse-off products / (a) 0,05 % Retinol Equivalent (RE) (b) 0,3 % RE · 标签措辞:For any cosmetic product containing Retinol, Retinyl Acetate or Retinyl Palmitate the following, labelling is obligatory: ‘Contains Vitamin A. Consider your dai ｜ [(2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohexen-1-yl)nona-2,4,6,8-tetraenyl] acetate (45) / Retinyl Acetate / 127-47-9 / 204-844-2 ｜ [(2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohexen-1-yl)nona-2,4,6,8-tetraenyl] hexadecanoate (45) / Retinyl Palmitate / 79-81-2 / 201-228-5 | EU Regulation 1223/2009 consolidated 2026-05-01 (EUR-Lex)C · Official source |
GCC Standardization OrganizationGSOApplies in 6 countries / territoriesSaudi Arabia · UAE · Oman · Qatar · Kuwait · Bahrain | RestrictedGSO 1943:2021 Annex → EU Annex III | 附录 III 限用 · 序号 376 · (a) Body lotion (b) other leave-on and rinse-off products / (a) 0,05 % Retinol Equivalent (RE) (b) 0,3 % RE · 标签措辞:For any cosmetic product… Show full text附录 III 限用 · 序号 376 · (a) Body lotion (b) other leave-on and rinse-off products / (a) 0,05 % Retinol Equivalent (RE) (b) 0,3 % RE · 标签措辞:For any cosmetic product containing Retinol, Retinyl Acetate or Retinyl Palmitate the following, labelling is obligatory: ‘Contains Vitamin A. Consider your dai ｜ [(2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohexen-1-yl)nona-2,4,6,8-tetraenyl] acetate (45) / Retinyl Acetate / 127-47-9 / 204-844-2 ｜ [(2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohexen-1-yl)nona-2,4,6,8-tetraenyl] hexadecanoate (45) / Retinyl Palmitate / 79-81-2 / 201-228-5 | GSO 1943:2021 Annex 2/3/4/5/6 → 动态引用 EU 1223/2009 附录(原文:listC · Official source |
GCC Standardization OrganizationGSOApplies in 6 countries / territoriesSaudi Arabia · UAE · Oman · Qatar · Kuwait · Bahrain | RestrictedGSO 1943:2021 Annex 3 Table 1 | Vitamin A and its esters; Retinyl acetate, Retinyl palmitate (Retinol) · Max. conc.: < 1 % retinol equivalents. NB: 1.0% w/w retinol is equivalent to 1.15% w/w … Show full textVitamin A and its esters; Retinyl acetate, Retinyl palmitate (Retinol) · Max. conc.: < 1 % retinol equivalents. NB: 1.0% w/w retinol is equivalent to 1.15% w/w retinyl acetate and to 1.83% w/w retinyl palmitate. · 警示语:Product should not be used by pregnant women | GSO 1943:2021 Annex 3 Table 1 Additional Restricted IngredieC · Official source |
Public regulatory text on file for 5 jurisdiction(s), covering 41 countries / territories once regional blocs are expanded. Other markets have no public data here — absence is neither approval nor prohibition. Table updated 2026-09-22.
Compiled from publicly published regulatory texts; conditions are reproduced as published, neither rewritten nor translated. The latest official announcement of the target market prevails — this table is a compiled reference, not a compliance conclusion. Matched on the INCI name; salts, esters and synonyms may be missed. Usability and labelling are for the brand and its responsible person to verify against the full text.
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Functions from EU CosIng and the China inventory; irritancy, comedogenicity and rating are our internal reading, not a regulatory conclusion. Structure and molecular data from PubChem.
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