TITANIUM DIOXIDE
二氧化钛
Also known as Titanium dioxide (CI 77891)
CAS 13463-67-7EC 236-675-5PubChem CID 26042
What it is and how it is used
Physical UV filter and colorant up to 25%; nano form requires attention
Status in national inventories
| China · Inventory of existing ingredients | 02210 | 按照《化妆品安全技术规范》要求使用 |
|---|---|---|
| China · STSC prohibited / restricted | CN-113/26 | 准用防晒剂(表5) · 序号 26 · 最大允许浓度 25% |
| EU · CosIng | 38617 | 功能 COLORANT, OPACIFYING, UV ABSORBER, UV FILTER · 限制 IV/143 VI/27 VI/27a (nano) |
| EU · CosIng | 97726 | 功能 UV FILTER · 附录 VI · 最高浓度 25%* *: In case of combined use of Titanium Dioxide and Titanium Dioxide (nano), the sum shall not exceed the limit given in column g (Maximum concentration in ready for use preparation) · 限制 <empty>; as a cons |
| EU · Annexes to 1223/2009 | III/321 | 附录 III 限用 · 序号 321 · (a) face products in loose powder form (b) hair aerosol spray products (c) other products / (a) 25 %; (b) 1,4 % for general consumers, and 1.1 % for professional use. / (a) (b) Only in the pigmentary form (c) Not to be |
| EU · Annexes to 1223/2009 | VI/27 | 附录 VI 准用防晒剂 · 序号 27 · 25 % (4) / Titanium dioxide in powder form containing 1 % or more of particles with aerodynamic diameter ≤ 10 μm, to be used in compliance with Annex III, No 321. For the product types under letter (c) of column (f) in |
| Korea · Safety standards | KR-2/1143 | 附录 2 限用 · 紫外线过滤剂 · 限量 25% |
| Brazil · ANVISA | BR-600/18 | 准用防晒剂 · RDC 600/2022 第 18 项 · 最大浓度 25% |
| United States · FDA | US-73.2575 | 21 CFR 73.2575 化妆品准用色素 · 免认证 · The color additive titanium dioxide may be safely used in cosmetics, including cosmetics intended for use in the ara of the eye, in amounts consistent with good manufacturing practice. |
Matched on the exact INCI name; salts, esters and synonyms may be missed. The latest official text prevails.
Regulatory status by market Prohibited / restricted / permitted — listing is not approval
Americas
| Market | Status | Limit | Conditions (as published) | Source |
|---|---|---|---|---|
| BrazilANVISA | PermittedUV filterRDC 600/2022 | — | 准用防晒剂 · RDC 600/2022 第 18 项 · 最大浓度 25% | ANVISA RDC 600/2022 · transcrição Cosmetoguia(官方 gov.br/bvsmC · Official source |
MercosurGrupo Mercado ComúnApplies in 4 countries / territoriesBrazil · Argentina · Uruguay · Paraguay | PermittedUV filterGMC 44/15 (filtros UV) nº 22 | leave-on 25% | Res. GMC 44/15 nº 22 · Dióxido de titânio TITANIUM DIOXIDE · 25% | Res. GMC 44/15 Lista de filtros ultravioleta · normas.mercosC · Official source |
| United States · CaliforniaCDPH | Listed onlyCSCP reportable ingredient | — | Reportable ingredient under the California Safe Cosmetics Act: reported to CDPH as known or suspected to cause cancer, birth defects, or other developmental or … Show full textReportable ingredient under the California Safe Cosmetics Act: reported to CDPH as known or suspected to cause cancer, birth defects, or other developmental or reproductive harm. Chemical name (as reported): Titanium dioxide; CAS 13463-67-7/1317-70-0/98084-96-9/1317-80-2; reported in 93564 product records from 457 companies; top categories: Makeup Products (non-permanent) | Nail Products | Skin Care Products; 10292 records discontinued/reformulated; reports 2009-06-17..2020-06-23. | ca-cdphC · Official source |
EMEA
| Market | Status | Limit | Conditions (as published) | Source |
|---|---|---|---|---|
Eurasian Economic UnionEurasian Economic CommissionApplies in 5 countries / territoriesRussia · Belarus · Kazakhstan · Armenia · Kyrgyzstan | PermittedUV filterТР ТС 009/2011 Приложение 5 | — | 25 процентов (4) | ТР ТС 009/2011 приложения 1-5, Решение Совета ЕЭК № 32 от 20C · Official source |
European UnionEuropean CommissionApplies in 30 countries / territoriesAustria · Belgium · Bulgaria · Croatia · Cyprus · Czechia · Denmark · Estonia · Finland · France · Germany · Greece · Hungary · Ireland · Italy · Latvia · Lithuania · Luxembourg · Malta · Netherlands · Poland · Portugal · Romania · Slovakia · Slovenia · Spain · Sweden · Norway · Iceland · Liechtenstein | PermittedUV filterEU Annex VI | — | 附录 VI 准用防晒剂 · 序号 27 · 25 % (4) / Titanium dioxide in powder form containing 1 % or more of particles with aerodynamic diameter ≤ 10 μm, to be used in compliance… Show full text附录 VI 准用防晒剂 · 序号 27 · 25 % (4) / Titanium dioxide in powder form containing 1 % or more of particles with aerodynamic diameter ≤ 10 μm, to be used in compliance with Annex III, No 321. For the product types under letter (c) of column (f) in Annex III, No 321, the maximum concentration in ready for use preparation provided in column (g) of this entry applies. ｜ ▼M34 | EU Regulation 1223/2009 consolidated 2026-05-01 (EUR-Lex)C · Official source |
GCC Standardization OrganizationGSOApplies in 6 countries / territoriesSaudi Arabia · UAE · Oman · Qatar · Kuwait · Bahrain | PermittedUV filterGSO 1943:2021 Annex → EU Annex VI | — | 附录 VI 准用防晒剂 · 序号 27 · 25 % (4) / Titanium dioxide in powder form containing 1 % or more of particles with aerodynamic diameter ≤ 10 μm, to be used in compliance… Show full text附录 VI 准用防晒剂 · 序号 27 · 25 % (4) / Titanium dioxide in powder form containing 1 % or more of particles with aerodynamic diameter ≤ 10 μm, to be used in compliance with Annex III, No 321. For the product types under letter (c) of column (f) in Annex III, No 321, the maximum concentration in ready for use preparation provided in column (g) of this entry applies. ｜ ▼M34 | GSO 1943:2021 Annex 2/3/4/5/6 → 动态引用 EU 1223/2009 附录(原文:listC · Official source |
| United KingdomOPSS | PermittedUV filterUK Annex VI | — | Titanium dioxide · Titanium Dioxide · 13463-67-7/ · 1317-70-0/ · 1317-80-2 · 236-675-5/ · 215-280-1/ · 215-282-2 · 25 % · UK Annex VI · No 27 | UK Cosmetics Regulation (assimilated Regulation (EC) No 1223C · Official source |
Public regulatory text on file for 7 jurisdiction(s), covering 51 countries / territories once regional blocs are expanded. Other markets have no public data here — absence is neither approval nor prohibition. Table updated 2026-09-22.
Compiled from publicly published regulatory texts; conditions are reproduced as published, neither rewritten nor translated. The latest official announcement of the target market prevails — this table is a compiled reference, not a compliance conclusion. Matched on the INCI name; salts, esters and synonyms may be missed. Usability and labelling are for the brand and its responsible person to verify against the full text.
Literature
- Correlating nanoscale titania structure with toxicity: a cytotoxicity and inflammatory response study with human dermal fibroblasts and human lung epithelial cells.Toxicological sciences : an official journal of the Society of Toxicology · 2006
In vitro, high-concentration nano-TiO2 induced cytotoxicity in dermal fibroblasts.
C · Official source
Bibliographic records and finding summaries come from public literature databases; research leads only, not efficacy claims.
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Functions from EU CosIng and the China inventory; irritancy, comedogenicity and rating are our internal reading, not a regulatory conclusion. Structure and molecular data from PubChem.
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